2015年新著——药物发现与发展：从分子到药物（英文版）

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"Drug Discovery and Development: From Molecules to Medicine" ed. by Omboon Vallisuta and Suleiman Olima
InTAvE | 03 June, 2015 | ISBN: 9535121286 9789535121282 | 319 pages | PDF | 19 MB

This book demonstrates that various expertise are essential for drug discovery including synthetic or natural drugs, clinical pharmacology, receptor identification, drug metabolism, pharmacodynamic and pharmacokinetic research.

The book covers diverse chapter topics in drug discovery: Natural Products as Sources of Leading Molecules in Drug Discovery; Oncology and Drug Discovery; Receptors Involvement in Drug Discovery; Management and Development of Drugs against Infectious Diseases; Advanced Methodology.

Contents
Preface
1 The Evolving Role of Natural Products from the Tropical Ra***rests as a Replenishable Source of New Drug Leads
2 Edible and Medicinal Mushrooms as Promising Agents in Cancer
3 Challenges of Patient Selection for Phase I Oncology Trials
4 Advanced Human In vitro Models for the Discovery and Development of Lung Cancer Therapies
5 Nuclear Receptor Modulators — Current Approaches and Future Perspectives
6 Lipids and Liposomes in the Enhancement of Health and Treatment of Disease
7 The Small Molecule Inhibitor of Protein Kinase Revolution for the Treatment of Rheumatoid Arthritis
8 Current Management and Novel Therapeutic Strategies to Combat Chronic Delta Hepatitis
9 Targeting Bacterial Persistence to Develop Therapeutics Against Infectious Disease
10 Assay Validation in High Throughput Screening - from Concept to Application
11 Structural Analogy — Direct Similarity Versus Topographical Complementarity
12 Clinical Trials in Paediatrics — Regulatory and Methodological Aspects

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